Testing existing drugs in new combinations for high-risk neuroblastoma
Testing whether a combination of drugs could reduce the risk of relapse and limit side effects.
Making antibody immunotherapy for neuroblastoma safer
Investigating how antibody immunotherapy causes pain and nerve damage.
Precision medicines for paediatric acute myeloid leukaemia
Finding which MEK inhibitors work best for children with acute myeloid leukaemia.
Exploring ‘Junk DNA’ to find undiscovered causes of cancer
Using a new way to measure genetic variation in key sections of noncoding DNA.
Using genetics to understand why acute myeloid leukaemia cells don’t respond to treatment
Looking at the genetics of bone marrow samples to see which genes affect resistance to treatment.
Using synthetic antibodies to treat diffuse midline gliomas
Creating antibodies in the lab to treat diffuse midline gliomas and testing their effectiveness.
A new targeted treatment for anaplastic large cell lymphoma
Stopping protein activity to stop anaplastic large cell lymphomas from growing.
What makes ependymoma in infants different?
Looking at molecular makeup and MRIs to characterise infant ependymoma.
Finding a low-cost way to detect endemic Burkitt Lymphoma earlier
Helping children in sub-Saharan Africa with endemic Burkitt Lymphoma get diagnosed earlier.