Using genetics to understand why acute myeloid leukaemia cells don’t respond to treatment
Looking at the genetics of bone marrow samples to see which genes affect resistance to treatment.
Targeting proteins to fight acute myeloid leukaemia
Understanding how proteins act inside acute myeloid leukaemia cells, to find new drug targets.
Finding a low-cost way to detect endemic Burkitt Lymphoma earlier
Helping children in sub-Saharan Africa with endemic Burkitt Lymphoma get diagnosed earlier.
Investigating immune cells in sarcoma tumours
Finding why immunotherapy doesn't work for some children with sarcoma tumours.
A new targeted treatment for anaplastic large cell lymphoma
Stopping protein activity to stop anaplastic large cell lymphomas from growing.
A better way of delivering drugs for acute myeloid leukaemia
Testing nanoparticles as a way of getting drugs where they are needed for acute myeloid leukaemia.
A new protein targeted treatment for B-cell lymphoma
Assessing whether blocking a protein's activity could improve survival and reduce side effects.
What makes ependymoma in infants different?
Looking at molecular makeup and MRIs to characterise infant ependymoma.
Using synthetic antibodies to treat diffuse midline gliomas
Creating antibodies in the lab to treat diffuse midline gliomas and testing their effectiveness.