Targeting metabolism in aggressive childhood blood cancers
Prof Jonathan Bond and Dr Marie-Claire Fitzgerald aim to find a treatment that can exploit a key weakness of acute myeloid leukaemia.
The Little Princess Trust funds research projects in partnership with CCLG, as the founding partner of the CCLG Research Funding Network.
This partnership combines our research funding and grant management expertise with The Little Princess Trust's fantastic fundraising to support world-class scientific research into childhood cancer.
Prof Jonathan Bond and Dr Marie-Claire Fitzgerald aim to find a treatment that can exploit a key weakness of acute myeloid leukaemia.
Professor Suzanne Turner will investigate the behaviour of individual lymphoma cells in order to find out why treatments fail.
Dr Shelby Barnett and Dr Geoff Shenton will monitor crucial drug levels in patients' blood in order to improve CAR T therapy protocols.
Dr Maria Teresa Esposito hopes to learn more about a gene called SET in leukaemia and will test the best medicines to fight it.
Dr Lucia Cottone at University College London hopes to understand how osteosarcoma cells become resistant to chemotherapy, which has a big impact on patient survival.
It is particularly difficult to treat some groups of childhood cancer patients, especially infants in their first weeks of life. This application is to fund this rapidly developing research programme for two years, involving the treatment of 150-200.
Looking at whether medicines that prevent circular DNA replication can help prevent relapse.
Testing a new type of targeted treatment that applies to multiple types of childhood cancers.
Studying how neuroblastoma cells and immune cells interact over time to see how the cancer adapts to treatment.
Looking at how cancer cells alter the scaffolding inside the body that organises cells in order to spread and make new tumours.
Creating an immunotherapy that can be delivered to patients more quickly and cost-effectively.
Testing medicines that can correct the genetic messages that help cancer cells grow out of control.
Our partnership supports hundreds of Little Princess Trust-funded projects, from developing new treatments to understanding the causes of cancer.