Repurposing alcohol-abuse medicines to treat brain tumours
Understanding how a repurposed drug attacks and kills diffuse midline glioma cells.
Stopping drug resistant processes in T-cell acute lymphoblastic leukaemia
Developing a test to select patients who can be treated with a new medicine that prevents steroid resistance.
Blocking processes which keep leukaemia cells alive
Investigating the possibility of combining a medicine that blocks the process with a medicine that triggers a cell's defensive response to treat ALL.
Blocking chemical reactions which keep ependymoma cells alive
Testing four medicines to see if they can shut down the metabolism of brain cancer cells grown in the lab
Delivering packaged drugs into paediatric brain tumours using ultrasound
Packing medicines into heat-sensitive liposomes to transport cancer treatments into the brain.
Testing existing drugs in new combinations for high-risk neuroblastoma
Testing whether a combination of drugs could reduce the risk of relapse and limit side effects.
International clinical trial to test the use of dye during children’s cancer surgery
Testing whether a dye called Indocyanine Green (ICG) can help surgeons identify tumours and lymph nodes during surgery.
The Nephrogreen study – can dye help surgeons remove kidney tumours?
Testing the use of green dye in surgery to remove kidney tumours.
Identifying new drugs for the treatment of retinoblastoma
Testing new targeted drugs for retinoblastoma to find new treatment options.