Identifying new treatment options for Burkitt lymphoma that doesn’t respond to treatment
Using Burkitt lymphoma models to find essential survival genes to target for therapy.
Understanding chemotherapy doesn’t work as well for some children with neuroblastoma
Investigating how cancer cells can keep dividing and why this makes it harder to treat.
Discovering what makes teenagers and young adults with soft tissue sarcomas different
Finding the biological differences between teenage and young adult cancers cells compared to older adults.
Creating a new combination treatment for children's brain tumours
Repurposing medicines to support a new type of immunotherapy for brain tumours.
Finding out how infant leukaemia cells interact with the immune system
Understanding how leukaemia cells enlist immune system cells to help them survive chemotherapy.
Using anti-depressants to improve immunotherapy for neuroblastoma
Using anti-depressants to prevent the body's immune system from fighting immunotherapy treatments.
Understanding how blood cancer develops and comes back after treatment in babies
Investigating how a protein changes the way leukaemia cells behave in babies.
Repurposing alcohol-abuse medicines to treat brain tumours
Understanding how a repurposed drug attacks and kills diffuse midline glioma cells.
Stopping drug resistant processes in T-cell acute lymphoblastic leukaemia
Developing a test to select patients who can be treated with a new medicine that prevents steroid resistance.