Our research projects

Looking at how medulloblastoma brain tumours use an amino acid, and whether blocking access to that resource would make cancer cells more susceptible to treatment.

Looking at the early stages of leukaemia that develops after treatment for other cancers to find out what changes occur and how to fight it.

Using two drugs to prevent an essential Wilms tumour protein interacting with a growth-promoting protein, and testing this treatment in patient samples.

Using Burkitt lymphoma models to find essential survival genes to target for therapy.

Testing whether treatment could be safely reduced for children with germinoma brain tumours

Investigating how cancer cells can keep dividing and why this makes it harder to treat.

Using anti-depressants to prevent the body's immune system from fighting immunotherapy treatments.

Repurposing medicines to support a new type of immunotherapy for brain tumours.

Looking at how a process called 'cut-and-run' leads to genetic errors, and how those errors could be prevented in order to prevent relapse in childhood leukaemia.