We have been funding expert research since 2016, aiming to ensure that every child and young person has a safe and effective treatment for their cancer, and that they can live long and happy lives post-treatment.
Finding out which changes to how DNA is read in neuroblastoma can give doctors more information about the cancer, and investigating whether these changes could be stopped through medicines.
Using two drugs to prevent an essential Wilms tumour protein interacting with a growth-promoting protein, and testing this treatment in patient samples.
Testing whether treatment could be safely reduced for children with germinoma brain tumours
Using Burkitt lymphoma models to find essential survival genes to target for therapy.
Investigating how cancer cells can keep dividing and why this makes it harder to treat.
Repurposing medicines to support a new type of immunotherapy for brain tumours.
Using anti-depressants to prevent the body's immune system from fighting immunotherapy treatments.
Looking at how a process called 'cut-and-run' leads to genetic errors, and how those errors could be prevented in order to prevent relapse in childhood leukaemia.
Finding a way to use immunotherapy against a high-risk type of childhood brain tumour.
