Our research projects

This research focuses on the development of novel drugs for the treatment of childhood brain tumours.

Osteosarcoma bone cancer affects teenagers, around half of whom die within 5-years of diagnosis. We think we can solve these problems by modifying immune cells called “gamma-delta T-cells”.

Examining whether a group of drugs called gliflozins could be used to treat T-ALL

Developing and delivering small molecule drug and immunotherapy combinations for MYC-driven medulloblastoma: Efficacy, evolution and exploitation.

An open label, single centre, single arm, prospective feasibility study evaluating the effectiveness of near-infrared fluorescence(NIRF)using indo-cyanine green(ICG)in intra-abdominal or intra-thoracic minimally invasive surgery(MIS)in paediatric oncology.

Investigating the preclinical efficacy of albendazole in paediatric acute myeloid leukaemia

Repurposing antihistamines to reduce treatment-related toxicity for children with WNT-medulloblastoma

Investigating repurposed drugs to decrease the progression of Ewing’s sarcoma

Enhancing CAR T-cell expansion and prolonged persistence for the effective treatment of paediatric medulloblastoma