Discovering what causes Ewing's sarcoma to spread

Project title: Identifying molecular drivers of disease progression in Ewing’s sarcoma

Funded by CCLG and CCLG Special Named Fund Kieran Maxwell Legacy
Lead investigator: Professor Matthew Allen, University of Cambridge
Funded July 2018
Award: £10,000.00

Ewing’s sarcoma (EWS) is a form of bone cancer that is typically seen in children and adolescents. Even with currentgeneration treatments, there is a high risk of subsequent spread (metastasis) of the tumour, usually to the lungs, liver and brain, and often with fatal consequences. Limiting metastasis in EWS will extend quality and quantity of life for these patients. This project will identify key genes and molecules that drive EWS metastasis, develop a test for measuring them, and establish the usefulness of this approach in a series of clinical specimens from the CCLG archive.