Discovering new blood-based signals for monitoring brain tumours in children
Dr Alina Pandele at the University of Nottingham hopes to find fragments cancer cell genetic code in the blood which can help doctors know when ependymoma grows back.
Using an asthma medicine to harness the immune system and prevent childhood leukaemia from returning
Dr Sophie Kellaway at the University of Nottingham is investigating whether an asthma drug could help provide a new, targeted treatment for acute myeloid leukaemia.
Developing new cancer treatment testing models for children with leukaemia
Dr Katrina Lappin aims to create a cost effective and more accurate acute myeloid leukaemia model to test treatments on.
Reading critical changes in neuroblastoma’s genetic messages
Dr Jodie Bojko at the University of Bristol hopes to understand how genetic instructions are altered in neuroblastoma, and how this impacts the cancer.
Establishing a new comprehensive blood test to monitor rhabdomyosarcoma in children
Dr Supriti Ghosh at The Institute of Cancer Research hopes to learn more about how to use tiny fragments of DNA from the blood to monitor rhabdomyosarcoma.
Creating innovative new treatments for childhood rhabdomyosarcoma by harnessing the body’s natural defence system
Dr Matthew Blunt aims to create and test immunotherapy treatments for rhabdomyosarcoma that are safer and more effective than chemotherapy.
Blocking the activity of an essential protein to treat T-cell acute lymphoblastic leukaemia
Dr Maarten Hoogenkamp will continue his work into blocking the EAAT1 protein, which is crucial for the growth of T-cell acute lymphoblastic leukaemia.
Looking for early signs on brain MRIs that can predict whether young people with ependymoma will go on to experience cognitive problems
Professor Shivaram Avula will identify markers in the brains of young people with brain tumours that will help predict the development of long-term side effects like learning and memory problems.
Targeting a protein to treat acute myeloid leukaemia in children
Dr Karen Keeshan is researching to see if removing or blocking a specific protein involved in acute myeloid leukaemia can help make it easier to treat.