Creating a new immunotherapy approach to fight aggressive medulloblastoma
Finding a way to use immunotherapy against a high-risk type of childhood brain tumour.
Repurposing alcohol-abuse medicines to treat brain tumours
Understanding how a repurposed drug attacks and kills diffuse midline glioma cells.
Blocking chemical reactions which keep ependymoma cells alive
Testing four medicines to see if they can shut down the metabolism of brain cancer cells grown in the lab
Delivering packaged drugs into paediatric brain tumours using ultrasound
Packing medicines into heat-sensitive liposomes to transport cancer treatments into the brain.
The glowing tumour trial for children with aggressive brain tumours
A clinical trial testing the use of the 'pink drink' dye in children with brain tumours.
Making antibody immunotherapy for neuroblastoma safer
Investigating how antibody immunotherapy causes pain and nerve damage.
What makes ependymoma in infants different?
Looking at molecular makeup and MRIs to characterise infant ependymoma.
Using synthetic antibodies to treat diffuse midline gliomas
Creating antibodies in the lab to treat diffuse midline gliomas and testing their effectiveness.
Paediatric Hepatic International Tumour Trial
Developing more effective treatments for patients who have a low chance of survival, while reducing treatment and side effects for other patients.